Epigenetics and Regeneration

Gebonden Engels 2019 9780128148792
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Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming.

As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics.

Specificaties

ISBN13:9780128148792
Taal:Engels
Bindwijze:Gebonden

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Inhoudsopgave

<p>1. Epigenetics and Regeneration: An Overview</p> <p>Section I: Epigenetics: molecular players and mechanisms<br>2. Dynamics and mechanisms of DNA methylation reprogramming<br>3. Histone modifications<br>4. Non-coding RNAs as Regulators of Gene Expression in Pluripotency and Differentiation<br>5. Organizing Principles for the Spatial Folding of Chromosomes</p> <p>Section II: Development, Reprogramming & Tissue regeneration<br>6. Epigenetics of early mammalian development: A Pathway to Regenerative Medicine<br>7. Somatic Cell Epigenetic Reprogramming: Molecular Mechanisms and Therapeutic Potential<br>8. Regenerative potential across species: An Eco-Evo-Devo Perspective</p> <p>Section III: Regenerative medicine: The epigenetics of tissue homeostasis, repair and regeneration<br>9. Common challenges in tissue regeneration<br>10. Epigenetic Mechanisms in Liver and Pancreas Generation and Regeneration<br>11. Transcriptional and Epigenetic Mechanisms Controlling Intestinal Cell Fate <br>12. Using Epigenetics as a Pharmacological Tool in Heart Regeneration<br>13. Epigenetic Regulation of Muscle Stem Cells During Skeletal Muscle Regeneration and Disease<br>14. The Intrinsic Role of Epigenetics in Axonal Regeneration <br>15. Insights Into the Epigenetics of Retinal Development and Diseases<br>16. At the Intersection of Epigenetics and Regeneration: An Analysis of the Experimental Outlook of Organoid Technology</p> <p>Section IV: Epigenetics, regeneration and environment<br>17. Epigenetic pharmacology in regenerative medicine (epi-drugs) <br>18. Genomic and Epigenomic Potential With Age: Genome, Epigenome, and the Epigenetic Clock<br>19. Epigenetics and Lifestyle: The Impact of Stress, Diet, and Social Habits on Tissue Homeostasis20. </p> <p>Section V: Conclusive Remarks <br>20. iPSC- and Organoid-Based Biomedicine at the Intersection of Epigenetics and Regeneration: Charting the Normative Contours of Emerging Biomedical Platforms</p> <p><br> </p>

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€ 211,00
Levertijd ongeveer 9 werkdagen
Gratis verzonden

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        Epigenetics and Regeneration