Molecular Biology in Blood Transfusion

Moderators and Speakers. Foreword. <strong>I. Diagnostic Aspects:</strong> Molecular Biology in Blood Transfusion - Introduction; H.G. Klein. Advances in blood Grouping - The Molecular Biology Approach; M.E. Reid. Molecular Biology in Parentage Testing and Forensic Medicine; R.W. Allen. Towards a Universla Blood Group - Manipulating the Molecular Structure of Blood Group Antigens; D.J. Anstee. HLA and HPA Typing - Advances in the Application of Molecular Biology; C.E.M. Voorter. Discussion. <strong>II. Virology and QC</strong> <strong>Aspects:</strong> Nucleic Acid Testing (NAT) of Blood and Plasma Donors; M.P. Busch. Routine Experience and Future Developments in Virus NAT Application; J. Coste. Developments of New Diagnostic Tools: Lateral Flow; H.A. Fields. The Relevance of Platelet CD62 (P-selectin) Testing; A.D. Michelson. The Recipient Mechanisms of Platelet Alloimmunisation; J.W. Semple. Towards Standardisation of CD34+ Cell Enumeration in Stem Cell Harvesting and Processing; W.H. Dzik. Discussion. <strong>III. Developments in Processing of Cells and Therapeutic</strong> <strong>Proteins:</strong> Applications of Molecular Biology in Stem Cell Transplantation; C.E. van der Schoot. The In Vitro Effects of Cytokines on Expansion and Maturation of Megakaryocyte Progenitor Cells; A.L. Drayer. A Closed Culture System for the Ex Vivo Transduction and Expansion of Human T Lymphocytes; E. Robinet. Recombinant Products for Haemostasis - Structure/Function Relationship; S.V. Seremetis. Application of Molecular Biology in the Engineering of IV Immunoglobulins; D.L. Siegel. Discussion. <strong>IV. New</strong> <strong>Horizons in Clinical Medicine:</strong> Targeted Immunotherapy - The Use of Dendritic Cells in Tumour Vaccines; G.A.P. Hospers. Use of In Vitro and In Vivo Genetically Manipulated Cells for Immunotherapy of Cancer; M.S. Mincheff. Clinical Outcomes and Future Perspectives of Umbilical Cord Stem Cell Transplants; J.E. Wagner. Strategies and Future Developments in Applied Molecular Biology (Closing Remarks); H.G. Klein. Discussion. Index