I. Repairable Damage in DNA.- 1. Repairable Damage in DNA: Overview.- 2. The Nature of the Alkylation Lesion in Mammalian Cells.- 3. “Excision” of Bases from DNA Methylated by Carcinogens in Vivo and Its Possible Significance in Mutagenesis and Carcinogenesis.- 4. Alkali-Labile Lesions in DNA from Cells Treated with Methylating Agents, 4-Nitroquinoline-N-oxide, or Ultraviolet Light.- 5. Apurinic and Apyrimidinic Sites in DNA.- 6. Maintenance of DNA and Repair of Apurinic Sites.- 7. DNA Turnover and Strand Breaks in Escherichia coli.- 8. Excision-Repair of ?-Ray-Damaged Thymine in Bacterial and Mammalian Systems.- 9. Formation of Dimers in Ultraviolet-Irradiated DNA.- 10. An Enzymatic Assay for Pyrimidine Dimers in DNA.- II. Enzymatic Photoreactivation.- 11. Enzymatic Photoreactivation: Overview.- 12. Kinetics of Photoreactivation.- 13. Purifying the Escherichia coliPhotoreactivating Enzyme.- 14. The Human Leukocyte Photoreactivating Enzyme.- 15. Photorepair of RNA.- III. Dark Repair in Bacteriophage Systems.- 16. Dark Repair in Bacteriophage Systems: Overview.- 17. Enzymic Mechanism of Excision-Repair in T4-Infected Cells.- 18. The Repair of Ultraviolet Damage by Phage T4: The Role of the Early Phage Genes.- 19. Repair of IIeteroduplex DNA in Bacteriophage T4.- 20. Recovery of Phage ? from Ultraviolet Damage.- IV. Enzymology of Excision-Repair in Bacteria.- 21. Enzymology of Excision-Repair in Bacteria: Overview.- 22. The Escherichia coliUV Endonuclease (Correndonuclease II).- 23. Endonuclease II of Escherichia coli.- 24. Endonuclease III: An Endonuclease from Escherichia coli That Introduces Single Polynucleotide Chain Scissions in Ultraviolet-Irradiated DNA.- 25. An Escherichia coliEndonuclease Which Acts on X-Irradiated DNA.- 26. Substrate Specificity ofMicrococcus luteus UV Endonuclease and Its Overlap with DNA Photolyase Activity.- 27. Two Temperature-Sensitive polA Mutants: An Approach to the Rolein Vivoof DNA Polymerase I.- 28. The Role of DNA Polymerase I in Excision-Repair.- 29. Involvement of Escherichia coliDNA Polymerase-I-Associated 5??3? Exonuclease in Excision-Repair of UV-Damaged DNA.- 30. Exonuclease VII of Escherichia coli.- 31. Enzymatic Repair of UV-Irradiated DNA in Vitro.- 32. Repair Replication in Permeabilized Escherichia coli.- 33. Requirement for uvrAB Function for Postirradiation DNA Synthesis in Vitro.- 34. DNA Polymerase II-Dependent DNA Synthesis in Toluenized Bacillus subtilis Cells.- V. Repair by Genetic Recombination in Bacteria.- 35. Repair by Genetic Recombination in Bacteria: Overview.- 36. Genetic Exchanges Induced by Structural Damage in Nonreplicating Phage ? DNA.- 37. The Beginning of an Investigation of the Role of recF in the Pathways of Metabolism of Ultraviolet-Irradiated DNA in Escherichia coli.- 38. The Degradation of Duplex DNA by the recBC DNase ofEscherichia coli.- 39. Analysis of Temperature-Sensitive recB and recC Mutations.- 40. Recombination and Postreplication Repair.- 41. Ultraviolet-Light-Induced Incorporation of Bromodeoxyuridine into Parental DNA of an Excision-Defective Mutant of Escherichia coli.- 42. Distribution of Pyrimidine Dimers During Postreplication Repair in UV-Irradiated Excision-Deficient Cells of Escherichia coli K12.- 43. Experiments on the Filling of Daughter-Strand Gaps During Post- replication Repair.- 44. Postreplication Repair Gap Filling in an Escherichia coli Strain Deficient in dnaB Gene Product.- 45. Involvement of uvrD, exrA, and recB Genes in the Control of the Postreplicational Repair Process.- 46. Replication and Expression ofConstructed Plasmid Chimeras in Transformed Escherichia coli-A Review.- VI. Relationships Among Repair, Mutagenesis, and Survival.- 47. Relationships Among Repair, Mutagenesis, and Survival: Overview.- 48. SOS Repair Hypothesis: Phenomenology of an Inducible DNA Repair Which Is Accompanied by Mutagenesis.- 49. Thermal Enhancement of Ultraviolet Mutability in a dnaB uvrA Derivative of Escherichia coli B/r: Evidence for Inducible Error-Prone Repair.- 50. lexB: A New Gene Governing Radiation Sensitivity and Lysogenic Induction in Escherichia coli K12.- 51. Indirect Suppression of Radiation Sensitivity of a recA? Strain of Escherichia coli K12.- 52. The Two-Lesion Hypothesis for UV-Induced Mutation in Relation to Recovery of Capacity for DNA Replication.- 53. The Effect of Genes Controlling Radiation Sensitivity on Chemical Mutagenesis in Yeast.- 54. Influence of Repair on the Specificity of Ultraviolet-Induced Reversion of an Ochre Allele of the Structural Gene for Iso- 1-cytochrome c.- 55. The Role of DNA Polymerase I in Genetic Recombination and Viability of Escherichia coli.- 56. The Role of the rec Genes in the Viability of Escherichia coliK12.- Author Index (to Parts A and B).- Subject Index (to Parts A and B).
