Inhibitors of the Ras Superfamily G-proteins, Part A

Gebonden Engels 2013 9780124167490
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Samenvatting

This special volume of The Enzymes is targeted toward researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This thematic volume discusses inhibitors of the Ras superfamily G-proteins.

Specificaties

ISBN13:9780124167490
Taal:Engels
Bindwijze:Gebonden

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Inhoudsopgave

<ol> <li>The Ras superfamily G-proteins <br>Fuyuhiko Tamanoi</li> <li>NMR Study to Identify a Ligand-Binding Pocket in Ras <br>Till Maurer and Weiru Wang</li> <li>The Allosteric Switch and Conformational States in Ras GTPase Affected by Small Molecules<br>Christian W. Johnson and Carla Mattos</li> <li>State 1(T) Inhibitors of Activated Ras<br>Hans Robert Kalbitzer and Michael Spoerner</li> <li>Sugar-Based Inhibitors of Ras Activation: Biological Activity and Identification of Ras-Inhibitor Binding Interface  <br>Alessandro Di Domizio and Francesco Peri </li> <li>Development of EHop-016, a Small Molecule Inhibitor of Rac<br>Suranganie Dharmawardhane </li> <li>Aptamer-Derived Peptide Inhibitors of Rho Guanine Nucleotide Exchange Factors <br>Susanne Schmidt and Anne Debant</li> <li>Targeting the Dbl and Dock-Family RhoGEFs: a Yeast-Based Assay to Identify Cell-Active Inhibitors of Rho-Controlled Pathways <br>Anne Blangy and Philippe Fort</li> <li>Inhibitors of the ROCK Serine/Threonine Kinases: Key Effectors of the RhoA Small GTPase<br>Dominico Vigil and Channing J. Der</li> <li>A Two-Hybrid Approach to Identify Inhibitors of the RAS-RAF Interaction<br>Vladimir Khazak, Susanne Eyrisch, Juran Kato, Fuyuhiko Tamanoi and Erica A. Golemis </li> <li>Inhibitors of K-Ras Plasma Membrane Localization<br>Kwang-jin Cho, Dharini van der Hoeven and John F. Hancock </li> <li>Ras Chaperons: New Targets for Cancer and Immunotherapy<br>Yoel Kloog, Galit Elad-Sfadia, Roni Haklai and Adam Mor <br></li></ol>

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€ 152,25
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        Inhibitors of the Ras Superfamily G-proteins, Part A