Inhibitors of the Ras Superfamily G-proteins, Part B

<ol> <li>Discovery of Small-Molecule Ras Inhibitors that Display Anti-Tumor Activity by Interfering with Ras•GTP-Effector InteractionFumi Shima, Yoko Yoshikawa, Shigeyuki Matsumoto and Tohru Kataoka</li> <li>An Orthosteric Inhibitor of the RAS-SOS InteractionSeth Nickerson, Stephen T. Joy, Paramjit S. Arora and Dafna Bar-Sagi </li> <li>Conformation-Specific Inhibitors of Raf kinasesXiaolun Wang and Kristin Schleicher</li> <li>Inhibitors of the ERK Mitogen-activated Protein Kinase Cascade for Targeting RAS Mutant CancersLeanna Gentry, Ahmed A. Samatar and Channing J. Der</li> <li>Inhibiting the RAS - PI3K Pathway in Cancer TherapyClare Sheridan and Julian Downward</li> <li>The RalGEF/Ral Pathway: Evaluating an Intervention Opportunity for Ras CancersJonathan M. Cooper, Brian O. Bodemann and Michael A. White</li> <li>p21-Activated Kinase InhibitorsJoachim Rudolph, James J. Crawford, Klaus P. Hoeflich, and Jonathan Chernoff</li> <li>Recent Progress in Developing Small Molecule Inhibitors Designed to Interfere with Ras Membrane Association: Towards Inhibiting K-Ras and N-Ras Functions Fuyuhiko Tamanoi and Jie Lu</li> <li>Synthetic Lethal Genetic Screens in Ras Mutant CancersBing Yu and Ji Luo</li></ol>