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Recent Advances in Medicinal Chemistry, Volume 1

Paperback Engels 2015 9780128039618
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Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more.

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ISBN13:9780128039618
Taal:Engels
Bindwijze:Paperback

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Inhoudsopgave

1. New Functions of Old Drugs: Aureolic Acid Group of Anti-Cancer Antibiotics and Non-Steroidal Anti-Inflammatory Drugs<br>2. Updated Report on a Novel Mercaptopyruvate Sulfurtransferase Thioredoxin-Dependent Redox-Sensing Molecular Switch: A Mechanism for the Maintenance of Cellular Redox Equilibrium<br>3. Characterization of Inorganic Nanomaterials as Therapeutic Vehicles<br>4. Aromatase Inhibitors: A New Reality for the Adjuvant Endocrine Treatment of Early-Stage Breast Cancer in Postmenopausal Women<br>5. Bacterial FabH: Towards the Discovery of New Broad-Spectrum Antibiotics<br>6. Tannins and their Influence on Health<br>7. Rho-GTPases and Statins: A Potential Target and a Potential Therapeutic Tool Against Tumors?<br>8. Carotenoids that are Involved in Prostate Cancer Risk<br>9. Preclinical Studies of Saponins for Tumor Therapy<br>10. Pharmacological Neuroprotection for Acute Spinal Cord Injury<br>11. HPLC and its Essential Role in the Analysis of Tricyclic Antidepressants in Biological Samples<br>12. Gene Expression Profiles in Breast Cancer to Identify Estrogen Receptor Target Genes<br>13. Trans-Plasma Membrane Electron Transport in Human Blood Platelets: An Update<br>14. Role of Intermediate States in Protein Folding and Misfolding

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        Recent Advances in Medicinal Chemistry, Volume 1