Prognostic Epigenetics

Gebonden Engels 2019 9780128142592
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Samenvatting

This volume provides comprehensive information on how mapping an individual’s epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can be applied in drug development and for better diagnosis and prognosis of diseases.

Prognostic Epigenetics is the most-inclusive volume to-date specifically dedicated to epigenetic markers that have been developed for prognosis of diseases, recent advances in this field, the clinical implementation of this research, and the future outlook.

Specificaties

ISBN13:9780128142592
Taal:Engels
Bindwijze:Gebonden

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Inhoudsopgave

1. It is more than simple genes: The epigenome is more powerful than your genome<br>2. Diagnostic, prognostic and therapeutic potential of the inter-individual variability in the major epigenetic processes: A Clinical Prospective<br>3. Technological advances in studying epigenetics biomarkers for clinical research<br>4. DNA methylation and Chromatin remodeling: Potential prognostic biomarker for disease diagnosis<br>5. Use of post-translational histone modifications for disease diagnosis<br>6. Use of non-coding RNAs as Clinical Biomarkers for disease diagnosis<br>7. The Epigenetic Landscape in Neurological and Neurodegenerative Disorders<br>8. Epigenetic Biomarkers in Asthma and Allergy<br>9. Epigenetics Biomarkers in Metabolic syndrome and Obesity<br>10. Chromatin landscape and Epigenetic biomarkers for clinical diagnosis and prognosis of Type 2 Diabetes mellitus<br>11. Epigenetic biomarkers in Cardiovascular disorders<br>12. Epigenetic biomarkers in Cancer<br>13. Epigenetics in Infectious diseases<br>14. Epigenetics of autoimmune disorders<br>15. Epigenetics of Birth defects<br>16. Epigenetics of adverse pregnancy outcomes<br>17. Epigenetic landscape of Infertility<br>18.  Epigenetic landscape of polycystic ovarian syndrome<br>19. Epigenetic biomarkers in ocular disorders<br>20. Epigenetic biomarkers in personalized medicine<br>21. Conclusions and Perspectives. Future Challenges and Prospects for Prognostic Epigenetics and personalized epigenomics

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€ 211,00
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        Prognostic Epigenetics