Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Optical Imaging and Conjugation

<ol> <ol> <li>Fluorogenic detection of protein aggregates in live cells using the AggTag method</li> <p>Kwan Ho Jung and Xin Zhang</p> <p> <li>Synthesis and application of a ratiometric probe for hydrogen peroxide</li> <p>Ruwen Yin, Yuan Fang, Xinqi Zhou and Cliff I. Stains</p> <p> <li>Protein labeling for FRET with methoxycoumarin and acridonylalanine</li> <p>Chloe M. Jones, Yarra Venkatesh and E. James Petersson</p> <p> <li>Ascertaining the activity and inhibition of adenosine deaminase via fluorescence-based assays</li> <p>Paul T. Ludford III and Yitzhak Tor</p> <p> <li>Method to discriminate amyloids using fluorescent probes</li> <p>Kristine L. Teppang, Rachel S. Ehrlich and Jerry Yang</p> <p> <li>Chemical modulation of circadian rhythms and assessment of cellular behavior via indirubin and derivatives </li> <p>Hui-Hsien Lin, Kelly L. Robertson, Sujeewa S. Lellupitiyage Don, Stephanie R. Taylor and Michelle E. Farkas</p> <p> <li>Methods for analysis of near-infrared (NIR) quenched-fluorescent contrast agents in mouse models of cancer</li> <p>John C. Widen, Martina Tholen, Joshua J. Yim and Matthew Bogyo</p> <p> <li>Acid-brightening fluorescent protein (abFP) for imaging acidic vesicles and organelles</li> <p>Nanxi Wang and Lei Wang</p> <p> <li>4-Cyanoindole-based fluorophores for biological spectroscopy and microscopy</li> <p>Arusha Acharyya, Ismail A. Ahmed and Feng Gai</p> <p> <li>Dissecting contributions of catalytic and reader domains in regulation of histone demethylation</li> <p>Nektaria Petronikolou, James E. Longbotham and Danica Galonić Fujimori</p> <p> <li>Ortho-Phthalaldehyde (OPA)-based chemoselective protein bioconjugation and peptide cyclization</li> <p>Qing Zhang, Yue Zhang and Xuechen Li</p> <p> <li>Chemical synthesis of di-ubiquitin modified histones for further biochemical studies</li> <p>Jia-Bin Li, Jun Liang and Changlin Tian</p> <p> <li>Chemical probes and methods for single-cell detection and quantification of epichaperomes in hematologic malignancies</li> <p>Swathi Merugu, Sahil Sharma, Justin Kaner, Chander Digwal, Mayumi Sugita, Suhasini Joshi, Tony Taldone, Monica L. Guzman and Gabriela Chiosis</p> <p> <li>FlICk (fluorescent isoindole crosslinking) for peptide stapling</li> <p>Mihajlo Todorovic and David M. Perrin</p> <p> <li>Selective protein N-terminal labeling with N-hydroxysuccinimide esters</li> <p>Hanjie Jiang, Gabriel D. D'Agostino, Philip A. Cole and Daniel R. Dempsey</p> <p> <li>Covalent live-cell labeling of proteins using a photoreactive fluorogen</li> <p>Tewoderos M. Ayele, Steve D. Knutson and Jennifer M. Heemstra</p> <p> <li>Photoconvertible diazaxanthilidene dyes for live cell imaging</li> <p>Rachel M. Lackner, Christopher L. Johnny and David M. Chenoweth</p> <p> <li>No-wash live cell imaging with a photoswitchable near-infrared hCRBPII protein-fluorophore tag</li> </ol></ol> <p>Wei Sheng, James H. Geiger and Babak Borhan</p>