Viral Replication Enzymes and their Inhibitors Part A

<p>Preface</p> <p>Craig E. Cameron, Jamie J. Arnold and Laurie S. Kaguni</p> <p>1. CoV-er all the bases: Structural perspectives of SARS-CoV-2 RNA synthesis</p> <p>Brandon Malone, Seth A. Darst and Elizabeth A. Campbell</p> <p>2. Mechanisms of inhibition of viral RNA replication by nucleotide analogs</p> <p>Kenneth A. Johnson and Tyler Dangerfield</p> <p>3. HCV RdRp, sofosbuvir and beyond</p> <p>Joy Y. Feng and Adrian S. Ray</p> <p>4. Understanding viral replication and transcription using single-molecule techniques</p> <p>Emmanuelle Pitre and Aartjan J.W. te Velthuis</p> <p>5. In vitro single-molecule manipulation studies of viral DNA replication</p> <p>Rebeca Bocanegra, Ismael Plaza-G.A. and Borja Ibarra</p> <p>6. Allosteric and dynamic control of RNA-dependent RNA polymerase function and fidelity</p> <p>Dennis S. Winston and David D. Boehr</p> <p>7. Single-cell analysis for the study of viral inhibitors</p> <p>Mohamad S. Sotoudegan, Jamie J. Arnold and Craig E. Cameron</p> <p>8. Structural basis of viral RNA-dependent RNA polymerase nucleotide addition cycle in picornaviruses</p> <p>Peng Gong</p> <p>9. Picornaviral 2C proteins: A unique ATPase family critical in virus replication</p> <p>Pu Chen, Zhijian Li and Sheng Cui</p> <p>10. Flavivirus enzymes and their inhibitors</p> <p>Ekaterina Knyazhanskaya, Marc C. Morais and Kyung H. Choi</p> <p>11. Watching the bacterial RNA polymerase transcription reaction by time-dependent soak-trigger-freeze X-Ray crystallography</p> <p>Yeonoh Shin and Katsuhiko S. Murakami</p> <p>12. Inhibition of viral RNA-dependent RNA polymerases with clinically relevant nucleotide analogs</p> <p>Kieran Maheden, Brendan Todd, Calvin J. Gordon, Egor P. Tchesnokov and Matthias Götte</p>