SECTION 1: NASAL CAVITY ANDPARANASAL SINUSES<br>4 Nose and Paranasal Sinuses<br>Lester D. R. Thompson, MD and Jonathan B. McHugh, MD<br>CONGENITAL/GENETIC/HEREDITARY <br>6 Nasal Neuroglial Heterotopia<br>Lester D. R. Thompson, MD<br>8 Nasal Dermoid Cyst and Sinus<br>INFECTIOUS <br>10 Allergic Fungal Sinusitis<br>14 Invasive Fungal Rhinosinusitis<br>16 Mycetoma<br>17 Rhinoscleroma<br>18 Rhinosporidiosis<br>20 Mycobacterium lepraeInfection<br>INFLAMMATORY-IMMUNE DYSFUNCTION <br>22 Chronic Rhinosinusitis<br>Brenda L. Nelson, DDS, MS<br>26 Granulomatosis With Polyangiitis<br>Susan Müller, DMD, MS<br>32 Eosinophilic Angiocentric Fibrosis<br>REACTIVE AND HAMARTOMAS <br>36 Sinonasal Inflammatory Polyp Brenda L. Nelson, DDS, MS and Lester D. R. Thompson, MD<br>40 Antrochoanal Polyp<br>Lester D. R. Thompson, MD and Brenda L. Nelson, DDS, MS<br>42 Mucocele of Paranasal Sinus<br>44 Sinonasal Hamartoma<br>Brenda L. Nelson, DDS, MS and Lester D. R. Thompson, MD<br>50 Nasal Chondromesenchymal Hamartoma<br>52 Extranodal Sinus Histiocytosis With Massive Lymphadenopathy<br>56 Myospherulosis<br>BENIGN NEOPLASM <br>58 Sinonasal Papilloma<br>66 Pleomorphic Adenoma, Sinonasal Tract<br>68 Meningioma, Sinonasal Tract<br>72 Ameloblastoma, Sinonasal Tract<br>74 Ectopic Pituitary Neuroendocrine Tumor<br>80 Lobular Capillary Hemangioma (Pyogenic Granuloma)<br>84 Sinonasal Tract Angiofibroma<br>88 Schwannoma/Neurofibroma, Sinonasal Tract<br>92 Leiomyoma and Smooth Muscle Tumors of Uncertain Malignant Potential<br>96 Fibromatosis/Desmoid-Type Fibromatosis<br>98 Solitary Fibrous Tumor, Sinonasal Tract<br>BORDERLINE NEOPLASM <br>102 Glomangiopericytoma<br>MALIGNANT NEOPLASM <br>106 Squamous Cell Carcinoma, Sinonasal Tract<br>114 NUT Carcinoma<br>116 SWI/SNF Complex-Deficient Sinonasal Carcinomas<br>120 Lymphoepithelial Carcinoma, Sinonasal Tract<br>122 Sinonasal Undifferentiated Carcinoma<br>128 Teratocarcinosarcoma<br>134 HPV-Related Multiphenotypic Sinonasal Carcinoma<br>138 Sinonasal Adenocarcinoma, Intestinal Type<br>144 Sinonasal Nonintestinal-Nonsalivary Adenocarcinoma<br>152 Sinonasal Renal Cell-Like Adenocarcinoma<br>154 Olfactory Neuroblastoma<br>164 Sinonasal Neuroendocrine Carcinoma<br>170 Mucosal Melanoma, Sinonasal Tract<br>176 Alveolar Rhabdomyosarcoma, Sinonasal Tract<br>182 Ewing Sarcoma, Including Sinonasal Adamantinoma-Like<br>188 Biphenotypic Sinonasal Sarcoma<br>192 Leiomyosarcoma, Sinonasal Tract<br>198 Malignant Peripheral Nerve Sheath Tumor, Sinonasal Tract<br>202 Fibrosarcoma, Sinonasal Tract<br>206 Angiosarcoma, Sinonasal Tract<br>210 Mesenchymal Chondrosarcoma, Sinonasal Tract<br>212 Undifferentiated Pleomorphic Sarcoma, Sinonasal Tract<br>216 Extranodal NK-/T-Cell Lymphoma, Nasal Type<br>Aaron Auerbach, MD, MPH<br>222 Metastatic/Secondary Tumors, Sinonasal Tract<br>SPECIMEN EXAMINATION, NASAL CAVITY & PARANASAL SINUSES <br>224 Specimen Examination and Staging Tools, Oropharynx<br>228 Specimen Examination and Staging Tools, Nasopharynx<br>SECTION 2: PHARYNX (NASAL, HYPO-)<br>234 Pharynx<br>236 Tornwaldt Cyst<br>237 Rathke Cleft Cyst<br>238 Dermoid<br>240 Low-Grade Nasopharyngeal Papillary Adenocarcinoma<br>244 Nasopharyngeal Carcinoma, Nonkeratinizing Types<br>Susan Müller, DMD, MS and Lester D. R. Thompson, MD<br>254 Nasopharyngeal Carcinoma, Keratinizing Type<br>256 Nasopharyngeal Carcinoma, Basaloid Squamous Cell Carcinoma<br>260 Diffuse Large B-Cell Lymphoma NOS<br>SECTION 3: LARYNX AND TRACHEA<br>266 Larynx<br>268 Laryngocele and Laryngeal Cysts<br>270 Tracheopathia Osteoplastica<br>272 Laryngitis: Viral, Bacterial, Fungal<br>REACTIVE <br>276 Vocal Cord Nodules and Polyps<br>280 Reactive Epithelial Changes<br>284 Contact Ulcer<br>286 Amyloid (Amyloidoma)<br>288 Squamous Papilloma<br>292 Granular Cell Tumor, Larynx<br>294 Adult Rhabdomyoma<br>296 Inflammatory Myofibroblastic Tumor<br>300 Paraganglioma, Larynx<br>302 Chondroma<br>304 EBV-Associated Smooth Muscle Tumor<br>306 Keratinizing Dysplasia and Carcinoma In Situ<br>314 Conventional Squamous Cell Carcinoma<br>322 Verrucous Carcinoma<br>326 Spindle Cell Squamous Cell Carcinoma<br>332 Papillary Squamous Cell Carcinoma<br>Lester D. R. Thompson, MD and Susan Müller, DMD, MS<br>336 Basaloid Squamous Cell Carcinoma<br>340 Adenosquamous Carcinoma<br>344 Neuroendocrine Neoplasms, Larynx<br>354 Chondrosarcoma<br>358 Metastatic/Secondary Tumors, Larynx and Trachea<br>SPECIMEN EXAMINATION, LARYNX <br>360 Specimen Examination and Staging Tools, Larynx and Trachea<br>SECTION 4: ORAL CAVITY<br>364 Tongue<br>366 Oral Mucosae<br>CONGENITAL/GENETIC/HEREDITARY<br>368 Ectopic (Lingual) Thyroid<br>370 White Sponge Nevus<br>372 Multifocal Epithelial Hyperplasia (Heck Disease)<br>374 Oral Hairy Leukoplakia<br>376 Oral Infections<br>380 Oral Syphilis<br>384 Aphthous Stomatitis<br>390 Pemphigus Vulgaris<br>392 Mucous Membrane Pemphigoid<br>394 Oral Lichen Planus<br>398 Erythema Multiforme<br>400 Lupus Erythematosus<br>404 Frictional Hyperkeratosis<br>405 Pseudoepitheliomatous Hyperplasia<br>406 Necrotizing Sialometaplasia<br>408 Traumatic Ulcerative Granuloma With Stromal Eosinophilia<br>410 Giant Cell Fibroma<br>411 Amalgam Tattoo<br>412 Tobacco Changes<br>414 Parulis<br>NONNEOPLASTIC LESIONS <br>415 Fordyce Granules<br>416 Mucocele and Ranula<br>418 Verruciform Xanthoma<br>419 Hairy Tongue<br>420 Geographic Tongue<br>422 Juxtaoral Organ of Chievitz<br>423 Heterotopic Salivary Glands<br>424 Squamous Papilloma (Including Verruca and Condyloma)<br>428 Fibroma, Oral Cavity<br>430 Pyogenic Granuloma<br>432 Peripheral Giant Cell Granuloma<br>434 Peripheral Ossifying Fibroma<br>436 Mucosal Neuroma<br>438 Solitary Circumscribed Neuroma<br>440 Acquired Melanocytic Nevus<br>444 Melanoacanthoma<br>445 Oral Lymphangioma<br>446 Teratoma, Oral Cavity<br>448 Congenital Granular Cell Epulis<br>450 Granular Cell Tumor, Oral Cavity<br>454 Melanotic Neuroectodermal Tumor of Infancy<br>456 Ectomesenchymal Chondromyxoid Tumor<br>460 GLI1-Altered Soft Tissue Tumor<br>462 Dysplasia and Carcinoma In Situ<br>468 Proliferative Verrucous Leukoplakia<br>470 Squamous Cell Carcinoma, Oral Cavity<br>476 Mucosal Melanoma, Oral Cavity<br>480 Extraskeletal Myxoid Chondrosarcoma<br>482 Angiosarcoma, Oral Cavity<br>484 Kaposi Sarcoma, Oral Cavity<br>486 Metastatic/Secondary Tumors: Oral Cavity; Jaw<br>SPECIMEN EXAMINATION, LIP AND ORAL CAVITY <br>488 Specimen Examination and Staging Tools, Lip and Oral Cavity<br>SECTION 5: OROPHARYNX<br>492 Infectious Mononucleosis<br>496 HIV Infection of Tonsils and Adenoids<br>500 Lymphangiomatous Polyp<br>502 Oropharyngeal Carcinoma<br>SECTION 6: SALIVARY GLANDS<br>508 Major Salivary Glands<br>510 HIV Salivary Gland Disease<br>512 Benign Lymphoepithelial Cyst<br>514 Benign Lymphoepithelial Lesion<br>516 Sjögren Syndrome Brenda L. Nelson, DDS, MS and Lester D. R. Thompson, MD<br>520 IgG4-Related Salivary Gland Disease<br>524 Oncocytosis (Oncocytic Hyperplasia)<br>525 Sialolithiasis<br>526 Pleomorphic Adenoma<br>536 Basal Cell Adenoma<br>540 Myoepithelioma<br>544 Warthin Tumor (Papillary Cystadenoma Lymphomatosum)<br>548 Oncocytoma<br>554 Canalicular Adenoma<br>556 Cystadenoma<br>558 Ductal Papillomas<br>562 Salivary Gland Adenoma: Lymphadenoma, Sebaceous Lymphadenoma, and Sebaceous Adenoma<br>564 Sclerosing Polycystic Adenoma<br>566 Keratocystoma<br>567 Sialolipoma<br>568 Hemangioma, Parotid Gland<br>570 Sialoblastoma<br>574 Mucoepidermoid Carcinoma, Salivary<br>584 Adenoid Cystic Carcinoma<br>592 Acinic Cell Carcinoma<br>600 Secretory Carcinoma, Salivary Gland<br>604 Microsecretory Adenocarcinoma<br>606 Polymorphous Adenocarcinoma, Low-Grade Subtype<br>612 Polymorphous Adenocarcinoma, Cribriform Subtype<br>614 Hyalinizing Clear Cell Carcinoma<br>620 Basal Cell Adenocarcinoma<br>624 Intraductal Carcinoma<br>626 Salivary Duct Carcinoma<br>636 Myoepithelial Carcinoma<br>640 Epithelial-Myoepithelial Carcinoma<br>646 Carcinoma Ex-Pleomorphic Adenoma<br>656 Mucinous Adenocarcinoma<br>660 Sclerosing Microcystic Adenocarcinoma<br>662 Lymphoepithelial Carcinoma, Salivary Gland<br>668 Sebaceous Carcinoma and Sebaceous Lymphadenocarcinoma<br>670 Adenocarcinoma, Not Otherwise Specified<br>672 Small Cell Neuroendocrine Carcinoma, Salivary Gland<br>676 Lymphoma, Salivary Gland<br>678 Metastatic/Secondary Tumors, Salivary Glands<br>SPECIMEN EXAMINATION, SALIVARY GLANDS <br>680 Specimen Examination and Staging Tools, Salivary Glands<br>SECTION 7: JAW<br>684 Teeth<br>686 Cherubism<br>REACTIVE/INFECTIOUS <br>688 Tori<br>690 Osteomyelitis<br>694 Osteonecrosis<br>698 Cemento-Osseous Dysplasia<br>700 Fibrous Dysplasia<br>704 Paget Disease of Bone<br>CYSTS <br>708 Simple Bone Cyst<br>710 Pseudocysts and Surgical Ciliated Cysts of Jaw<br>712 Periapical Cyst/Granuloma<br>714 Nasopalatine Duct Cyst<br>716 Dentigerous Cyst<br>720 Orthokeratinized Odontogenic Cyst<br>722 Lateral Periodontal Cyst<br>724 Calcifying Odontogenic Cyst<br>726 Glandular Odontogenic Cyst<br>728 Odontogenic Keratocyst<br>732 Adenomatoid Odontogenic Tumor<br>734 Squamous Odontogenic Tumor<br>736 Calcifying Epithelial Odontogenic Tumor<br>738 Ameloblastoma, Jaw<br>744 Odontoma (Complex and Compound)<br>746 Ameloblastic Fibroma/Fibroodontoma<br>748 Odontogenic Fibroma<br>750 Cementoblastoma<br>752 Odontogenic Myxoma<br>754 Central Giant Cell Granuloma<br>756 Ossifying Fibroma, Jaw<br>760 Juvenile Active Ossifying Fibroma<br>764 Osteoma<br>766 Osteoblastoma<br>768 Ameloblastic Carcinoma<br>770 Clear Cell Odontogenic Carcinoma<br>772 Ghost Cell Odontogenic Carcinoma<br>774 Ameloblastic Fibrosarcoma<br>776 Osteosarcoma, Jaw<br>780 Chondrosarcoma, Jaw<br>786 Plasma Cell Myeloma, Jaw<br>SECTION 8: EAR AND TEMPORAL BONE<br>790 Ear<br>792 Accessory Tragus<br>794 Encephalocele<br>796 First Branchial Cleft Anomaly<br>800 Otitis Media<br>802 Necrotizing Otitis Externa<br>804 Chondrodermatitis Nodularis Chronica Helicis<br>806 Otic Polyp<br>808 Relapsing Polychondritis<br>DEGENERATIVE <br>810 Cystic Chondromalacia (Auricular Pseudocyst)<br>812 Otosclerosis<br>METABOLIC <br>814 Gout<br>816 Exostosis<br>818 Keloid<br>David Cassarino, MD, PhD and Lester D. R. Thompson, MD<br>820 Synovial Chondromatosis (Temporomandibular Joint)<br>822 Ceruminous Adenoma<br>826 Cholesteatoma<br>830 Jugulotympanic Paraganglioma<br>836 Vestibular Schwannoma<br>840 Meningioma, Ear and Temporal Bone<br>842 Epithelioid Hemangioma<br>844 Middle Ear Neuroendocrine Tumor<br>850 Endolymphatic Sac Tumor<br>854 Langerhans Cell Histiocytosis, Ear and Temporal Bone<br>856 Atypical Fibroxanthoma<br>860 Squamous Cell Carcinoma, Ear and Temporal Bone<br>Lester D. R. Thompson, MD and David Cassarino, MD, PhD<br>864 Basal Cell Carcinoma<br>866 Merkel Cell Carcinoma<br>870 Dermatofibrosarcoma Protuberans<br>874 Ceruminous Adenocarcinoma<br>878 Rhabdomyosarcoma, Ear and Temporal Bone<br>882 Metastatic/Secondary Tumors, Ear and Temporal Bone<br>SECTION 9: NECK (SOFT TISSUE ANDLYMPH NODES)<br>886 Lymph Nodes<br>888 Branchial Cleft Cyst<br>894 Dermoid Cyst<br>896 Cervical Thymic Cyst<br>898 Bronchogenic Cyst<br>900 Cat-Scratch Disease<br>904 Bacillary Angiomatosis<br>906 Mycobacterial Spindle Cell Pseudotumor<br>908 Sarcoidosis<br>910 Nodular Fasciitis<br>912 Lymphangioma, Neck<br>914 Lipoma<br>916 Spindle Cell Lipoma<br>918 Hibernoma<br>920 Lipoblastoma<br>922 Elastofibroma<br>924 Perineurioma<br>928 Fetal Rhabdomyoma<br>932 Nuchal-Type Fibroma<br>934 Branchioma (Ectopic Hamartomatous Thymoma)<br>936 Carotid Body Paraganglioma<br>942 Metastatic Cystic Squamous Cell Carcinoma<br>948 Synovial Sarcoma<br>954 Chordoma<br>960 Liposarcoma<br>SECTION 10: THYROID GLAND<br>966 Thyroid Gland<br>968 Thyroglossal Duct Cyst<br>972 Ectopic Thyroid Gland<br>974 Solid Cell Nests<br>976 Dyshormonogenetic Goiter<br>980 Infectious Thyroiditis<br>INFLAMMATORY-IMMUNE DYSFUNCTION<br>984 Palpation Thyroiditis<br>986 Subacute Granulomatous Thyroiditis (de Quervain)<br>992 Chronic Lymphocytic (Hashimoto) Thyroiditis<br>998 Graves Disease (Diffuse Hyperplasia)<br>1004 Amyloid Goiter<br>1008 IgG4-Related Thyroiditis<br>1010 Multinodular Hyperplasia<br>1018 Pigments and Crystals in Thyroid Gland<br>1020 Post Thyroid Biopsy Changes<br>1024 C-Cell Hyperplasia (Physiologic)<br>1026 Radiation Thyroiditis<br>1028 Follicular Adenoma<br>1034 Follicular Adenoma With Papillary Architecture<br>1038 Oncocytic Follicular Adenoma<br>1042 Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclei<br>1046 Hyalinizing Trabecular Tumor<br>1050 Thyroid Teratoma<br>1054 Paraganglioma, Thyroid Gland<br>1056 Solitary Fibrous Tumor, Thyroid Gland<br>1060 Leiomyoma, Thyroid Gland<br>1062 Schwannoma, Thyroid Gland<br>1064 Langerhans Cell Histiocytosis, Thyroid Gland<br>1068 Ovarian Thyroid Tissue<br>1072 Papillary Thyroid Carcinoma<br>1088 Follicular Thyroid Carcinoma<br>1100 Oncocytic Follicular Thyroid Carcinoma<br>1106 High-Grade Follicular-Derived Thyroid Carcinomas<br>1114 Undifferentiated (Anaplastic) Thyroid Carcinoma<br>1122 Medullary Thyroid Carcinoma<br>1134 Thyroblastoma<br>1136 Mucoepidermoid Carcinoma, Thyroid Gland<br>1140 Sclerosing Mucoepidermoid Carcinoma With Eosinophilia<br>1144 Cribriform Morular Thyroid Carcinoma<br>1146 Spindle Epithelial Tumor With Thymus-Like Elements<br>1150 Thymic Carcinoma Family Thyroid Tumors<br>1154 Angiosarcoma, Thyroid Gland<br>1158 Leiomyosarcoma, Thyroid Gland<br>1162 Malignant Peripheral Nerve Sheath Tumor, Thyroid Gland<br>1166 Follicular Dendritic Cell Sarcoma, Thyroid Gland<br>1170 Lymphoma, Thyroid Gland<br>1180 Metastatic/Secondary Tumors, Thyroid Gland<br>SPECIMEN EXAMINATION, THYROID GLAND <br>1186 Specimen Examination and Staging Tools, Thyroid Gland<br>SECTION 11: PARATHYROID GLANDS<br>1190 Parathyroid<br>NONNEOPLASTIC <br>1192 Parathyroid Hyperplasia<br>1200 Tertiary Hyperparathyroidism<br>1201 Chronic Parathyroiditis<br>1202 Parathyroid Adenoma<br>1210 Parathyroid Carcinoma<br>1216 Metastatic/Secondary Tumors, Parathyroid Glands