Advances in Molecular Pathology, 2021

Current Tools, Databases, and Resources for Phenotype and Variant Analysis of Clinical Exome Sequencing<br>Applications of Noninvasive Prenatal Testing for Subchromosomal Copy Number Variations Using Cell-Free DNA<br>Applications of Optical Genome Mapping in Next-Generation Cytogenetics and Genomics<br>Diagnosis of Variant Translocations in Acute Promyelocytic Leukemia<br>Next-Generation Sequencing for Measurable Residual Disease Assessment in Acute Leukemia<br>Molecular Profile of BCR-ABL1 Negative Myeloproliferative Neoplasms and Its Impact on Prognosis and Management<br>Engineering Consideration for Emerging Essential Nucleic Acid Tests for Point-of>Care Diagnostics<br>The Importance of Use of Genetics to Guide Hypertension Therapy: Using b>Blockade as an Example<br>Emerging Molecular Diagnostic Methods for Prosthetic Joint Infections<br>The Role of the Human Gutome on Chronic Disease: A Review of the Microbiome and Nutrigenomics<br>Blood Group Genotyping<br>Artificial Intelligence in Anatomic Pathology<br>Cell-free Nucleic Acids in Cancer: Current Approaches, Challenges, and Future Directions<br>Tumor Mutational Burden Calculation and Microsatellite Instability Detection in Clinical Next-Generation Sequencing Assays<br>Operationalizing Genomic Medicine: Laboratory Practice Considerations Beyond the Assay<br>A PENNdemic Year in Review<br>Review of SARS-CoV-2 Antigen and Antibody Testing in Diagnosis and Community Surveillance<br>The Genomic Landscape of Severe Acute Respiratory Syndrome Coronavirus 2: Surveillance of Variants of Concern