Killer Cell Dynamics

Mathematical and Computational Approaches to Immunology

Gebonden Engels 2006 2007e druk 9780387308937
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Samenvatting

This book reviews how mathematical and computational approaches can be useful to help us understand how killer T-cell responses work to fight viral infections. It also demonstrates, in a writing style that exemplifies the point, that such mathematical and computational approaches are most valuable when coupled with experimental work through interdisciplinary collaborations. Designed to be useful to immunoligists and viroligists without extensive computational background, the book covers a broad variety of topics, including both basic immunological questions and the application of these insights to the understanding and treatment of pathogenic human diseases.

Specificaties

ISBN13:9780387308937
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:220
Uitgever:Springer New York
Druk:2007

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Inhoudsopgave

Viruses and Immune Responses: A Dynamical View.- Models of CTL Responses and Correlates of Virus Control.- CTL Memory.- CD4 T Cell Help.- Immunodominance.- Multiple Infections and CTL Dynamics.- Control versus CTL-Induced Pathology.- Lytic versus Nonlytic Activity.- Dynamical Interactions between CTL and Antibody Responses.- Effector Molecules and CTL Homeostasis.- Virus-Induced Subversion of CTL Responses.- Boosting Immunity against Immunosuppressive Infections.- Evolutionary Aspects of Immunity.

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€ 156,99
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        Killer Cell Dynamics