Qiao-Hong Chen,
Qiao-Hong (Professor and Graduate Coordinator, Department of Chemistry and Biochemistry, California State University, California, USA) Chen
Anti-Prostate Cancer Agents
Paperback Engels 2025 9780443235856Levertijd ongeveer 9 werkdagen
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Samenvatting
Anti-Prostate Cancer Agents walks the readers through the anti-prostate cancer drug development pipeline from early discovery/design to clinical studies/applications. This book covers discovery/design, synthetic studies, preclinical evaluation, mechanism of action, structure-activity relationships, clinical studies/applications of anti-prostate cancer agents.
This book provides insight on how the design and discovery process of anti-prostate cancer agents have evolved from androgen deprivation therapy to current androgen receptor antagonists/degraders. So far, no book focusing on the topic has been published.
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Inhoudsopgave
<p>1. Introduction: Overview of Prostate Cancer <br>2. Why has one got prostate cancer?<br>3. Androgen Deprivation Therapy<br>4. Anti-prostate cancer agents interacting with topoisomerase<br>5. Microtubule-Stabilizing Compounds as Anti-Prostate Cancer Agents<br>6. Androgen/Androgen Receptor Signaling Pathway and Prostate Cancer <br>7. Anti-Prostate Cancer Agents Suppressing Androgen Biosynthesis <br>8. First Generation Nonsteroidal Androgen Receptor Antagonists <br>9. Second Generation Nonsteroidal Androgen Receptor Antagonists<br>10. Anti-Prostate Cancer Agents Interacting with N-Terminal Domain of Androgen Receptor<br>11. Androgen Receptor Degraders as Anti-Prostate Cancer Agents<br>12. Radiotherapeutics for treatment of Prostate Cancer<br>13. Immunotherapy for Prostate Cancer<br>14. Radiosensitizer for prostate cancer <br>15. Anti-Prostate Cancer Agents Targeting Prostate-Specific Membrane Antigen<br>16. Anti-Prostate Cancer Agents Targeting Poly(ADP-Ribose)Polymerase<br>17. Combined Anti-Prostate Cancer Agents<br>18. Future Directions </p>
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