Pharmacology and Therapeutics in the New Millennium

Preface. <strong>1.</strong> Endothelial Dysfunction and Vascular Disease; P.M. Vanhoutte. <strong>2.</strong> Endothelin Receptors: Targets for drug development; A. Ray, et al. <strong>3.</strong> Role of Endothelins in Cardiovascular Disease; L.C. Katwa. <strong>4.</strong> The Diabetic Vasculature and Endothelin; D.A. Misurski, et al. <strong>5.</strong> Beneficial Effects of Renin-Angiotensin System Blockade in Myocardial Infarction; N.S. Dhalla, X. Guo. <strong>6.</strong> Role of Angiotensinogen in Human Hypertension; A. Kumar. <strong>7.</strong> Biological Function of Cardiac High Molecular Weight Calmodulin-binding Protein; R. Kakkar, et al. <strong>8.</strong> A Synthetic Calmodulin-binding Peptide Unmasks Crucial Calmodulin Control of the Calcium-Pumping ATPase in Cardiac Sarcoplasmic Reticulum; N. Narayanan, A. Xu. <strong>9.</strong> Pharmacology of Vascular Adenosine Receptors; M.A.H. Talukder, et al. <strong>10.</strong> Aquaretic Vasopressin Antagonists to Treat Chronic Hyponatremia; C.N. Corder, et al. <strong>11.</strong> Regional Differences in the Regulation of L-type Calcium Current in Heart Cells; R. Kumar, et al. <strong>12.</strong> Domoic Acid as a Tool in Molecular Pharmacology; S.K. Sharma, N.S. Dhalla. <strong>13.</strong> Molecular Basis of Adapted Heart; D.K. Das, N. Maulik. <strong>14.</strong> Gene Therapy and Renin-Angiotensin System; A.S. Pachori, et al. <strong>15.</strong> Transgenic and Knockout Mouse Models in New Drug Discovery; V. Kumar. <strong>16.</strong> Epidermal Growth Factor Receptor mRNA in Prostate: Clinical Implications and Hormonal Regulation; V.L. Kumar. <strong>17.</strong> Angiogenesis: Concepts and Research Methodologies; S. Sengupta, S.K. Gupta. <strong>18.</strong> Metabolism-Based Antifolate Drug Design: MDAM and MTREX; A. Amato, et al. <strong>19.</strong> Angiogenesis: A New Approach to Glutamine Related Therapy; P. Maity, P. Bhattacharya. <strong>20.</strong> Isolation and Characterization of Apoptosis Resistant Mutants: Molecular Targets for Chemoprevention; N. Singh, et al. <strong>21.</strong> High Exposure to Caffeine-Derived N-Nitroso Compounds as Carcinogenic Risk for G.I.T. Cancers in Kashmir; M. Siddiqi. <strong>22.</strong> Regulation of N-Myristoyl-transferase in Human Colon Cancer; R.V.S. Rajala, et al. <strong>23.</strong> Differential Activation and Inhibition of Calmodulin-Dependent Cyclic Nucleotide Phosphodiesterase Isozymes; R.K. Sharma. <strong>24.</strong> Antioxidants in the Prevention of Hypercholesterolemic Atherosclerosis; P. Lee, K. Prasad. <strong>25.</strong> Oxidative Stress and Aniline-Induced Splenic Toxicity; M.F. Khan, G.A.S. Ansari. <strong>26.</strong> Efficacy of High Dose Multiple Antioxidants as an Adjunct to Standard Cancer Therapy; K.N. Prasad, et al. <strong>27.</strong> Carotenoid/Retinol Dosage in Prevention/Treatment of Second Primary Cancer, Cyclical Mastodynia Syndrome and AIDS; L. Santamaria, A. Bianchi-Santamaria. <strong>28.</strong> Complimentary Medicines and 21st Century Therapeutics: Challenges for Pharmacologists; D.B.A. Narayana, R.M. Dobriyal. <strong>29.</strong> Strategies to Identify New Compounds and Pharmacological Activities from Traditional Herbal Medicines in Single and Combined Usage; I. Kimura, M. Kimura. <strong>30.</strong> Plant-Derived Agents Against Cancer; F. Abdullaev. <strong>31.</strong> Antidiabetic Effect of Viayasar (Pterocarpus marsupium); R.R. Chaudhury. <strong>32.</strong> Development of Hepatoprotective Formulation from Plant Sources; S.S. Agrawal. <strong>33.</strong> Kava <(Piper methysticum): From a Pacific Island Curiosity to a Herbal Superstar; Y.N. Singh. <strong>34.</strong> Antiproliferative and Chemopreventive Potential of Indian Medicinal Plants, Withania somnifera and Ocimum sanctum; S.K. Gupta, J. Prakash. <strong>35.</strong> Antiepileptic Drug Therapy in the New Millennium; Y.K. Gupta, J. Malhotra. <strong>36.</strong> Neurochemical Abnormalities in the Hippocampal Formation with Schizophrenia; E. Scarr. <strong>37.</strong> Changes in the Dopaminergic and Serotonergic Systems of the Prefrontal Cortex in Subjects with Schizophrenia: Evidence from Postmortem Stuides; B. Dean. <strong>38.</strong> The Mammalian Metabotropic GABA£Y<strong>/Y£ Receptor and Its Role; N.G. Bowery. <strong>39.</strong> Signal-Transducing Activity of the Natriuretic Peptide C Receptor (NPR-C) in Neuronal Tissue; G.J. Trachte. <strong>40.</strong> Carotenoid Interactions with Cellular Isoprenoid Pathways: A Common Mechanistic Theme for Diverse Biological Activities; W.C. Cole, K.N. Prasad. <strong>14.</strong> Psychotherapeutic Implications of Cooperation and Control-Operations Among Multiple Opioid Receptors; K.K. Sharma, P.K. Mediratta. <strong>42.</strong> Opioid Gastrointestinal Dependence; T.F. Burks, et al. <strong>43.</strong> A Role for Calcium-Activated Neutral Proteinase in Myelin Protein Degradation Associated with Optic Neuritis and Multiple Sclerosis; D.C. Shields, N.L. Banik. <strong>44.</strong> Myelin Galactosphingolipids as Negative Regulators of Differentiation; R. Bansal. <strong>45.</strong> The Need for Pharmacovigilance; S. Olsson. <strong>46.</strong> Pharmacovigilance and its Status in India; S.K. Gupta, U. Singh. <strong>47.</strong> Pharmacovigilance and Detection of Signals; A. Misra, S. Sinha. <strong>48.</strong> Reinforcing Drug Safety and Pharmacovigilance in Graduate Medical Curriculum; M. Thomas. <strong>49.</strong> Treatment of Viral Pneumonia using a Combination of Antiviral and Antiinflammatory Medications; G.A. Prince. <strong>50.</strong> Environmental Pollutants and Certain Therapeutic Agents Enhance the Severity of Virus Infection: Role of Cytokines; P. Seth, et al. <strong>51.</strong> Inhibitory Effect of Interferon on Sexual Stages of Simian Malaria Parasites in Rhesus Monkeys; R. Tripathi, et al. <strong>52.</strong> Therapeutic Strategies for Prevention of Cataract; S.K. Gupta, S. Joshi. <strong>53.</strong> Reversal of Cholinergic Response of Intraocular Muscles by Atropine: Drug Antagonism Re-examined; P.N. Patil. <strong>54.</strong> The Changing Target in the Treatment of Peptic Ulcer: From pH to Hp; U. Klotz. <strong>55.</strong> Nitric Oxide and Peroxynitrite in Airway Disease; F.P. Nijkamp, G. Folkerts. <strong>56.</strong> Therapeutic Agents for Benign Prostatic Hyperplasia: Achieving Pharmacological Selectivity; J.P. Hieble, A.C. Sulpizio. <strong>57.</strong> Pharmacology Teaching, Learning and Testing at Academic Institutions; P.N. Patil. <strong>58.</strong> Strategies for Reduction of Anthracycline Cardiac Toxicity; M.U.R. Naidu. <strong>59.</strong> Cyclooxygenase Isoenzymes: Their Selective Inhibitors; S.K. Kulkarni, et al. <strong>60.</strong> Contribution of the Clinical Pharmacologist to Control of Tropical Diseases; N.A. Kshirsagar, N.J. Gogtay. <strong>61.</strong> Glutathione S-Transferases: Some New Functional Roles; U. Pandya, et al. <strong>62.</strong> Catalytic Mechanism of mGSTA4-4, An Enzyme Involved in Response to Oxidative Stress; S.P. Singh, et al. <strong>63.</strong> Xenobiotic Conjugates of Fatty Acids; B.S. Kaphalia, et al. <strong>64.</strong> Aldose Reductase Efficeintly Detoxifies Lipid Derived Aldehydes; S.K. Srivastava, et al. <strong>65.</strong> Identity of RLIP76 with the ATP-Dependent Transporter for Glutathione Conjugates and Doxorubicin in Human Tissues; S. Awasthi, et al. <strong>66.</strong> The Protein Tyrosine Phosphatase Inhibitor Vanadyl Sulfate Prlongs Insulin-induced Activation of Mitogen-activated Protein Kinases ERK 1 and ERK 2 as well as Phosphatidylinositol-3-Kinase; J.-F. Th&eacute;berge, et al. Index.