Genomics-Driven Healthcare

Trends in Disease Prevention and Treatment

Paperback Engels 2018 9789811339592
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

This book evaluates trends arising in “-Omics” sciences in terms of their current and potential future application to therapeutic design and understanding of disease. Chapters consider the impact of pharmacogenomics and bioinformatics on drug development, as well as trends in genomics, as applied to understanding of neurodegenerative and lung disease, psychiatry and oncology.Following the genome studies released in early part of this century, the advent of the -Omics sciences (genomics and pharmacogenomics, proteomics, metabolomics, transcriptomics) has seen the expansion of a vast knowledgebase with utility in preventing and treating disease, and improving health for all. Bioinformatics and improved pharmacogenetic understanding forge a path for improved drug discovery and design methods accounting for differences in delivery and disposition across populations.

Specificaties

ISBN13:9789811339592
Taal:Engels
Bindwijze:paperback
Uitgever:Springer Nature Singapore

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Inhoudsopgave

<p>Chapter 1. Rethinking drug discovery and targeting after the genomic revolution</p>

<p>Dharmesh R Chejara, Ravindra V Badhe, Pradeep Kumar, Yahya E Choonara, Lomas K Tomar, Charu Tyagi, Viness Pillay</p>

<p>&nbsp;</p>

<p>Chapter 2. Living between sickness and health: Where is the human genome leading us?</p>

<p>Amy Broadwater, Yashwant Pathak</p>

<p>&nbsp;</p>

<p>Chapter 3. Pharmacogenomics: Setting Newer Paradigms of Genetics in Therapy and Medicine</p>

<p>Sanjay Dey, Kumud Joshi, Bhaskar Mazumder</p>

<p>&nbsp;</p>

<p>Chapter 4. Bioinformatics and Pharmacogenomics: Tools to Understand and Accelerate Infectious Disease Control</p>

Ashwani sharma, Subrata Sinha, Surabhi Johari, Bhaskar Mazumder<p></p>

<p>&nbsp;</p>

<p>Chapter 5. Race and Ethnicity – Understanding Difference in the Genome Era</p>

<p>Shannon Kelly, Yashwant Pathak</p>

<p>&nbsp;</p>

<p>Chapter 6. The Food Metabolome and Novel Dietary Biomarkers Associated with Diseases</p>

<p>Orhan E Arslan, Philip Palmon</p>

<p>&nbsp;</p>

<p>Chapter 7. Impact of genomics on drug discovery and clinical medicine</p>

<p>Deepak Gupta</p>

<p>&nbsp;</p>

<p>Chapter 8. Genomics and drug transporters and application in drug discovery, delivery and development</p>

<p>Robert Gharavi, Hazem E. Hassan</p>

<p>&nbsp;</p>

<p>Chapter 9. Genomics and drug metabolizing enzymes its application in Drug delivery: Evaluating the influence of the microbiome</p>

<p>Sheeba Varghese Gupta</p>

<p>&nbsp;</p>

<p>Chapter 10. Essentials of Genomics in the Continuum of Translational Research</p>

<p>Sadaf Aslam</p>

<p>&nbsp;</p>

<p>Chapter 11. Charting a course for genomic medicine from base pair to bedside</p>

<p>Teresa Vo</p>

<p>&nbsp;</p>

<p>Chapter 12. Pharmacogenomics and pharmacoepigenomics: impact on therapeutic strategies</p>

<p>Kristopher R Hall, Tamer E. Fandy</p>

<p>&nbsp;</p>

<p>Chapter 13. Clinical Pharmacogenomics and Personalized Medicine: New strategies to maximize drug efficacy and avoid adverse drug reaction</p>

<p>Chonlaphat Sukasem, Sadeep Medhasi</p>

<p>&nbsp;</p>

<p>Chapter 14. Epigenetic Patterns/Therapies associated with Genetic Disorders</p>

<p>Mazzio Elizabeth, Soliman KFA</p>

<p>&nbsp;</p>

<p>Chapter 15. Neurodegenerative disease conditions and genomic treatment&nbsp; for better health</p>

<p>Ravindra V. Badhe, Dharmesh R. Chejara, Pradeep Kumar, Yahya E. Choonara, Viness Pillay</p>

<p>&nbsp;</p>

<p>&nbsp;</p>

<p>Chapter 16. Recent Trends in -Omics based methods and techniques for Lung Diseases prevention</p>

<p>Raisah Salhab, Yashwant V Pathak</p>

<p>&nbsp;</p>

<p>Chapter 17. Impact of Genomics on Personalization of Breast Cancer Care</p>

<p>F. Scott Heinemann, Alice Police, Erin Lin, Mandy Liu, Sherry Liang, Ying Huang</p>

<p>&nbsp;</p>

<p>Chapter 18. Pharmacogenomics: a new approach for preventing severe cutaneous adverse drug reactions</p>

<p>Chonlaphat Sukasem, Therdpong Tempark</p>

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