A unique book that integrates knowledge from a wide range of expertise, specifically applied to the mouse, and addressed at a wide audience from those new to the field to experts who want an update on the state of the art.  Meer

Caenorhabditis Elegans has been a popular model organism for biological research for over thirty years and has been used to investigate many aspects of animal development, for example apoptosis, the Hox genes, signal transduction pathways, and the development of the nervous system.  Meer

With the complete genomes of many organisms now available, and the first draft of the human genome imminent, there is an increasing demand from researchers in a range of disciplines for techniques that will allow them to utilize these resources in their own research.  Meer

DNA microarrays, or biochips, are small glass chips embedded with ordered rows of DNA and by providing a massive parallel platform for data gathering represent a fundamental technical advance in biomedical research.  Meer

The first edition of this book established itself as the most widely used, concise guide to the most frequently used procedures in clinical microbiology laboratories.  Meer

New and updated, this second edition of Protein Structure presents electrophoretic, chromatographic, and spectrophotometric techniques as well as including new chapters on the relatively sophisticated methods of mass spectrometry and ultracentrifugation.  Meer

Protein Expression: A Practical Approach and its companion volume Post-translational Modification: A Practical Approach complete the mini-series of Practical Approach books covering the synthesis and subsequent processing of proteins.  Meer

Biomolecules and cells are critical components of biosensors and biomaterials, but in order to function in an artificial environment, they must be immobilized in a manner that does not affect their interaction with target analytes.  Meer

This new edition of Gel Electrophoresis of Proteins is a completely new text, with eight of the ten chapters written by new authors. It presents the best methods, hints and tips for core procedures such as one- dimensional polyacrylamide gel electrophoresis, isoelectric focusing, two-dimensional gel electrophoresis, preparative gel electrophoresis, and peptide mapping, complete with the latest refinements and updates of the procedures.  Meer

The most common aim of a biosensor is to produce a signal proportional in strength or frequency to the concentration of chemical or biochemical to which the biological element reacts.  Meer

This book is the final part of a trilogy of volumes covering the practical aspects of ligand interactions, biochemistry, and effector mechanisms of signal-transducing receptors.  Meer

Advances in the understanding of cellular processes at the molecular level have transformed the biological sciences. Plant pathology is a field which has benefited dramatically from the application of molecular techniques and has become one of the most exciting areas of biology today.  Meer

Protein engineering is the rational modification or redesign of proteins using genetic engineering. Thus, it is now possible to modify enzyme specifities, remodel antibodies, and redesign many multi-domain proteins for therapeutic purposes.  Meer

Although most often considered in terms of the generation of action potentials, there are several other electrical, metabolic and ionic correlates of neuronal activity.  Meer

Anaerobes are diverse and fascinating organisms. Due to recent advances in equipment and methodology researchers are now able to make increasingly widespread studies of their activities.  Meer

Acquired chromosome abnormalities are associated with malignancy, exposure to mutagenic agents, and some chromosome instability syndomes. Their study often entails extensive modification of standard cytogenetic techniques as well as a very different approach to analysis.  Meer

This is a concise yet comprehensive practical manual, enabling all those involved in the diagnosis of disease, caused by parasites, to provide both a competent and up-to-date service.  Meer

The topics collected in this volume present classical and molecular techniques currently used in medical virology for the diagnosis of viral infections and for further analysis of virus-specific antibodies and of clinical virus isolates.  Meer

Histocompatibility Testing: A Practical Approach describes methods for the investigation of Mhc at the gene and protein levels and their application to the clinical transplanation of human organs and bone marrow.  Meer

Plant cell culture techniques are being increasingly used in basic research and for plant exploitation in industry (genetic engineering, micropropagation).  Meer