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Serie: Progress in inflammation research
paperbackEngels9783034895729
29-10-2012
Cytokines have become established as key mediators of the signs and
symptoms of inflammatory diseases such as arthritis, dermatitis, asthma
and multiple sclerosis. Meer
paperbackEngels9783034895750
23-10-2012
Over the past ten years, a number of cytokines and growth factors have
proven to be as effective therapeutics. While these products have
certainly established recombinant biologics as a major pharmaceutical
growth sector, the continued interest in this class of drugs arises from
the fact that today we have a far better understanding of the human
immune response, both at a cellular and molecular level. Meer
paperbackEngels9783034895781
1-11-2012
Combinatorial chemistry in conjunction with High Throughput Screening
(HTS) is revolutionizing the drug discovery process. Yet, we have much
to learn about the integration of these powerful techniques with
information from genomics, proteomics, computation and pharmacokinetics
before dramatic increases in the drug discovery/development processes
can be achieved. Meer
paperbackEngels9783034895798
29-10-2012
Allergic skin diseases belong to the most common dermatoses. This book
deals with fundamental (in particular immunological aspects) as well as
clinical symptoms and therapeutic strategies of the allergic skin
diseases. Meer
paperbackEngels9783034895804
29-10-2012
In November 1998 many of the key leaders of new drug discovery for
inflammatory diseases gathered at Hershey, Pennsylvania for the 9th
International Conference of the Inflammation Research Association. Meer
paperbackEngels9783034896252
21-10-2012
In recent years, the area of pharmacotherapy of GI inflammation has witnessed important progress, with new drugs and therapeutic approaches being introduced. Meer
paperbackEngels9783034896283
23-10-2012
Chronic obstructive pulmonary disease (COPD) ranges amongst the commonest diseases in the world. The relentless progression of the disease causes a pressing need for a better understanding of and therapies for COPD. Meer
paperbackEngels9783034897525
14-10-2012
Apoptosis is a form of cell death that occurs in a controlled manner and is generally noninflammatory in nature. Apoptosis, or programmed cell death, implies a cell death that is part of a normal physiological process of pruning of unneeded cells. Meer
paperbackEngels9783034897532
1-11-2012
The book will provide an overview of the roles of vascular adhesion molecules in health and disease, with chapters on their cell biology, followed by chapters reviewing their importance in specific disease processes. Meer
paperbackEngels9783034897556
14-10-2012
This volume will be of great value to all those researchers in the area of the inflam matory response, notably academics, clinicians and members of the pharmaceutical industry. Meer
gebondenEngels9783031177736
5-1-2023
The volume summarizes the most recent advances in our understanding of the mesentery and explains the how these are important in inflammation. It comprises a series of state of the art chapters by leading authorities in each area. Meer
gebondenEngels9783030563189
31-10-2020
TLR4 is one of the most important innate immunity receptors, its function mainly consisting in the activation of inflammatory pathways in response to stimulation by Pathogen-Associated Molecular Patterns (PAMPs) and Damage Associated Molecular Pattern molecules (DAMPs). Meer
gebondenEngels9783030393342
8-4-2020
Perinatal psychiatry is an emerging field that investigates the role of perinatal events – for example pregnancy complications and infections – in the development of neuropsychiatric conditions, such as schizophrenia and mood disorders. Meer
paperbackEngels9783034897242
10-10-2012
This volume describes recent research in the field of metalloproteinases (a family of enzymes that can catalyze tissue degradation), in particular their participation in autoimmune diseases such as rheumatoid arthritis, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates. Meer
paperbackEngels9783034897365
23-10-2012
Many new antileukotriene drugs are now marketed as antiasthma drugs and
represent the first new drugs in this field since the 1970s. This book
covers the steps that have led to the discovery and development of these
new drugs and offers detailed descriptions of their clinical
applications. Meer
paperbackEngels9783034897563
29-10-2012
Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Meer
paperbackEngels9783034897570
5-11-2012
For some years, international guidelines on the management of asthma have stressed the importance of early intervention with anti-inflammatory drugs to prevent acute asthma exacerbations and to avert chronic inflammatory damage to the airway. Meer
paperbackEngels9783034897587
10-10-2012
Pain and inflammation are inextricably linked phenomena. The observation that chemical mediators with combined pro-inflammatory, algesic and/or hyperalgesic activity occur at the site of inflammation is fundamental not only to our present understanding of the inflammatory process but also to our attempts to devise clini cally useful anti-inflammatory therapies. Meer
paperbackEngels9783034897594
8-10-2012
t Heinz Red! and Gunther Sch!ag Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria The word "sepsis" derives from the Greek meaning decay or rottenness. Meer
paperbackEngels9783034897877
5-11-2012
Rheumatoid arthritis (RA) is the most common and most severe form of inflammatory arthritis. The pathogenesis of RA has been the subject of intense research for several decades. Meer