Genomics-Driven Healthcare
Trends in Disease Prevention and Treatment
Gebonden Engels 2018 9789811075056Samenvatting
This book evaluates trends arising in “-Omics” sciences in terms of their current and potential future application to therapeutic design and understanding of disease. Chapters consider the impact of pharmacogenomics and bioinformatics on drug development, as well as trends in genomics, as applied to understanding of neurodegenerative and lung disease, psychiatry and oncology.Following the genome studies released in early part of this century, the advent of the -Omics sciences (genomics and pharmacogenomics, proteomics, metabolomics, transcriptomics) has seen the expansion of a vast knowledgebase with utility in preventing and treating disease, and improving health for all. Bioinformatics and improved pharmacogenetic understanding forge a path for improved drug discovery and design methods accounting for differences in delivery and disposition across populations.
Specificaties
Lezersrecensies
Inhoudsopgave
Dharmesh R Chejara, Ravindra V Badhe, Pradeep Kumar, Yahya E Choonara, Lomas K Tomar, Charu Tyagi, Viness Pillay
Chapter 2. Living between sickness and health: Where is the human genome leading us?
Amy Broadwater, Yashwant Pathak
Chapter 3. Pharmacogenomics: Setting Newer Paradigms of Genetics in Therapy and Medicine
Sanjay Dey, Kumud Joshi, Bhaskar Mazumder
Chapter 4. Bioinformatics and Pharmacogenomics: Tools to Understand and Accelerate Infectious Disease Control
Ashwani sharma, Subrata Sinha, Surabhi Johari, Bhaskar Mazumder
Chapter 5. Race and Ethnicity – Understanding Difference in the Genome Era
Shannon Kelly, Yashwant Pathak
Chapter 6. The Food Metabolome and Novel Dietary Biomarkers Associated with Diseases
Orhan E Arslan, Philip Palmon
Chapter 7. Impact of genomics on drug discovery and clinical medicine
Deepak Gupta
Chapter 8. Genomics and drug transporters and application in drug discovery, delivery and development
Robert Gharavi, Hazem E. Hassan
Chapter 9. Genomics and drug metabolizing enzymes its application in Drug delivery: Evaluating the influence of the microbiome
Sheeba Varghese Gupta
Chapter 10. Essentials of Genomics in the Continuum of Translational Research
Sadaf Aslam
Chapter 11. Charting a course for genomic medicine from base pair to bedside
Teresa Vo
Chapter 12. Pharmacogenomics and pharmacoepigenomics: impact on therapeutic strategies
Kristopher R Hall, Tamer E. Fandy
Chapter 13. Clinical Pharmacogenomics and Personalized Medicine: New strategies to maximize drug efficacy and avoid adverse drug reaction
Chonlaphat Sukasem, Sadeep Medhasi
Chapter 14. Epigenetic Patterns/Therapies associated with Genetic Disorders
Mazzio Elizabeth, Soliman KFA
Chapter 15. Neurodegenerative disease conditions and genomic treatment for better health
Ravindra V. Badhe, Dharmesh R. Chejara, Pradeep Kumar, Yahya E. Choonara, Viness Pillay
Chapter 16. Recent Trends in -Omics based methods and techniques for Lung Diseases prevention
Raisah Salhab, Yashwant V Pathak
Chapter 17. Impact of Genomics on Personalization of Breast Cancer Care
F. Scott Heinemann, Alice Police, Erin Lin, Mandy Liu, Sherry Liang, Ying Huang
Chapter 18. Pharmacogenomics: a new approach for preventing severe cutaneous adverse drug reactions
Chonlaphat Sukasem, Therdpong Tempark
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